When you take one or two caplets of Travelan® before a meal, the anti-bacteria antibodies in the product lay in wait in the gastrointestinal tract. If you consume food or drinks that are contaminated with Travellers’ Diarrhoea causing bacteria, Travelan® utilises specific antibodies to bind the bacteria and the toxins they produce effectively neutralising them and inhibiting their attachment to the gastrointestinal tract reducing LPS-related inflammation and bacterial colonisation.
In short, Travelan® works to target and neutralise the bacteria and the toxins they produce before they can make you sick and ruin your holiday plans.
Travelan® contains bovine colostrum, a dairy product. The bovine colostrum in Travelan® is harvested from New Zealand dairy cows, which are certified to be free from bovine spongiform encephalopathy (BSE) a progressive neurological disorder of cattle. Each batch is pasteurised and tested to be free of antibiotics and microorganisms.
Travelan® contains cow’s milk proteins and lactose. Therefore do not take Travelan® if you have an allergy to bovine protein or are lactose intolerance due to the presence of milk protein and lactose.
Please read the label before use.
Travelan® contains the natural ingredient bovine colostrum powder, harvested from New Zealand dairy cows, and that are subject to a proprietary immunisation regime with proprietary vaccines to produce high levels of antibodies against specific strains of Enterotoxigenic E.coli (ETEC) bacteria and the toxins they produce, the most common cause of Travellers’ Diarrhoea.
In Australia Travelan® is listed in the ARTG, AUST L 106709.
Its indications are:
- Reduces the risk of Travellers’ Diarrhoea
- Reduces the risk of minor gastro-intestinal disorders
- Antimicrobial
In Canada Travelan® is registered as a Natural Health product (NPN 80046016). It is indicated to reduce the risk of Travellers’ Diarrhoea.
Travelan® has been sold over-the-counter in Australian pharmacies since September 2004.
Travellers’ Diarrhoea (TD) continues to be the most frequent health problem in travellers1.
According to the Centers for Disease Control and Prevention, Travellers’ Diarrhoea is a clinical disease resulting from microbial contamination of ingested food and water2. It occurs during or shortly after travel, most commonly affecting people travelling from an area of more highly developed hygiene and sanitation infrastructure to a less developed one.
Travellers’ Diarrhoea is characterised by the fairly abrupt onset of loose, watery or semi-formed stools associated with abdominal cramps and rectal urgency. Symptoms may be preceded by gaseousness, abdominal cramping, vomiting and fever. In almost a third of Travellers’ Diarrhoea victims, the symptoms will be severe enough to confine them to bed. The most common cause of Travellers’ Diarrhoea is the Enterotoxigenic E.coli ( ETEC ) which may be found in drinks, ice cubes, on the outside of fruits and vegetables, one the surface of utensils and anywhere contaminated water or poor hygiene is present. E.coli can be found in a street side stall or in the best restaurants.
To assist with the prevention of Travellers Diarrhoea, particularly when travelling to high-risk locations, we suggest the following:
- Don’t eat, under cooked or uncooked food.
- Only eat fruit that you can peel.
- Don’t drink tap water. Drink Bottled water
- Clean your teeth with bottled water.
- Don’t have ice in your drinks.
- Clean your hands with a hand wash substance often.
- Take Travelan as directed on the pack.
Clinical trials were designed to protect against Travellers’ Diarrhoea causing bacteria in volunteers challenged with ETEC. In these Controlled Human Infection Model (CHIM) studies healthy volunteers were given Travelan® caplets before being challenged with the ETEC bacteria.
You may also take Travelan® soon after food or drink intake. Additional caplets may be taken when increased cover is required, e.g. when snacking between meals or if circumstances suggest an increased risk of infection.
Travelan® is not indicated for use in children under 6 years of age except on professional health advice. The whole caplet may be difficult for children to ingest if they are under 6 years of age. The caplets are easily broken in half or crushed into a powder for easier administration.
Travelan® is not indicated for use by pregnant women since no human safety data was gathered in such patients..
Yes. Travelan® may decrease the severity of the symptoms of Travellers’ Diarrhoea, so it is recommended to continue to take the product if you get diarrhoea. Once you are suffering from TD, appropriate treatment should be started. It is also important to note that diarrhoea may relate to Travellers’ Diarrhoea disease but diarrhoea may also arise as occasional reactions to non-disease conditions, such as unfamiliar foods, stressful situations, overindulgence, and other changes in routines and circumstances that disturb the normal functioning of the intestinal tract. While such symptoms can occur in any place or time, travellers are susceptible because they are more likely, in general, to encounter the very conditions that can give rise to intestinal upset.
Travelan® does not contain colourings, flavourings or artificial coatings.
Travelan® contains bovine milk proteins, lactose and glucose.
The amount of lactose in Travelan® has been reduced by membrane filtration to less than 10%, compared to about 50% of dry weight skim milk powder.
The average amount of lactose per caplet is approximately 12mg, which is a daily dose of 36mg if 3 caplets are consumed in one day. This is well below the level at which clinical signs are usually experienced. However, those who are allergic to milk may likely react to Travelan®.
The amount of glucose per caplet is only 50mg, which means a daily dose of approx. 150mg if 3 caplets are consumed in one day. Travelan® has been tested and shown to be gluten free and does not contain artificial colourings, flavourings or coatings.
Travelan® was found in the clinical trials to significantly decrease the severity of the symptoms if someone does get Travellers’ Diarrhoea. Travelan® binds to ETEC and blocks their attachment to the gastrointestinal wall and this may help reduce re-colonisation and also reduce the time of infection and speed up recovery. Travelan® cannot “cure diarrhoea” but may assist in recovery and reduce the severity of the symptoms. It is also important to note that diarrhoea may relate to Travellers’ Diarrhoea disease but diarrhoea may also arise as occasional reactions to non-disease conditions, such as unfamiliar foods, stressful situations, overindulgence, and other changes in routines and circumstances that disturb the normal functioning of the intestinal tract. While such symptoms can occur in any place or time, travellers are susceptible because they are more likely, in general, to encounter the very conditions that can give rise to intestinal upset.
According to the Centers for Disease Control and Prevention Travellers’ Diarrhoea is a clinical syndrome resulting from microbial contamination of ingested food and water.
Travelan® utilises specific antibodies to bind the bacteria and the toxins they produce effectively neutralising them and inhibiting their attachment to the gastrointestinal tract reducing LPS-related inflammation and bacterial colonisation.
Enzymes: May assist in digestion but do not specifically target pathogenic bacteria.
Probiotics: The use of probiotics for the prevention of TD is controversial and suffers from a lack of well- controlled studies. Probiotics may enhance the body’s ability to withstand intestinal tract upsets, including diarrhea but do not specifically target or neutralise pathogenic bacteria which cause Travellers’ Diarrhoea.
- Travelan® is not known to be associated with any drug-drug interactions (DDI).
- As it is a non-absorbable product that acts locally on the gut immune system, it has a very high safety profile.
- However, any question with regard to potential DDI for specific drugs should be discussed with the primary care physician.
Travelan® is indicated to reduce the risk of Travellers’ Diarrhoea.
Travelan® targets the bacteria associated with most cases of bacteria-mediated diarrhoea, and its potential to reduce inflammation, suggests that it may be helpful in alleviating existing disease, and shortening the time to recovery. It is also important to note that diarrhoea may relate to Travellers’ Diarrhoea disease, but diarrhoea may also arise as occasional reactions to non-disease conditions, such as unfamiliar foods, stressful situations, overindulgence, and other changes in routines and circumstances that disturb the normal functioning of the intestinal tract. While such symptoms can occur in any place or time, travellers are susceptible because they are more likely, in general, to encounter the very conditions that can give rise to intestinal upset.
- Colostrum has some antibacterial and immune modulatory properties.
- However, Travelan® has in addition to the colostrum-derived compounds very high concentration of anti-E.coli antibodies.
- Travelan® utilises specific antibodies to bind the bacteria and the toxins they produce effectively neutralising them and inhibiting their attachment to the gastrointestinal tract reducing LPS-related inflammation and bacterial.
- These antibodies target the major bacteria which cause Travellers’ Diarrhoea.
- Travelan® has a unique synergistic effect between the colostrum-derived products and the high concentration antibodies for suppressing the inflammation and targeting the bacteria which cause Travellers’ Diarrhoea in the gastrointestinal system.
Travellers’ Diarrhoea is a disease typically caused by pathogenic bacteria contamination of ingested food and water which can strike down even the most experienced traveller. So how can I reduce the risk of getting Travellers’ Diarrhoea?
To assist in the prevention of Travellers’ Diarrhoea hand hygiene is a high priority. Wash your hands prior to eating and preparing food. Travellers’ Diarrhea is transmitted by food and water that has been contaminated by faeces.
Other tips to reduce the risk include:
- Don’t eat, under cooked or uncooked food.
- Only eat fruit that you can peel.
- Don’t drink tap water. Drink Bottled water
- Clean your teeth with bottled water.
- Don’t have ice in your drinks.
- Clean your hands with a hand wash substance often.
- Take Travelan as directed on the pack.
Yes. Immuron has partnered with Synlait, an innovative and trusted dairy company based in New Zealand, for the supply of its bovine colostrum powder. Synlait specializes in the processing of infant formula and special milk powders and operates under an internationally accredited ISO/IEC 17065 dairy assurance system. Synlait only partners with certified dairy farmers which exceed New Zealand’s Animal Health and Welfare standards. In addition to this, Immuron’s commercial operations are managed by experienced and qualified veterinarians. A small portion of colostrum is harvested from selected dairy farms for processing, leaving plenty for the calves and standard dairy farm requirements. The health and welfare of a herd impacts directly on milk quality. The best dairy farmers know this and work hard to ensure a happy, healthy herd. It’s the proactive steps they take today that help improve milk production tomorrow. Click here for more information on Synlait’s Lead with Pride programme.